Anti-OX40 Antibody

SKU: orb1675206

Description

OX40 or CD134 is encoded by the TNFRSF4 gene, a member of the TNF-receptor superfamily. Expression of OX40 is found in activated CD4 and CD8 T cells, but is absent in resting naïve T cells and most resting memory T cells. Anti-OX40 Antibody detects the presence of OX40, which plays a major role in proliferation and differentiation of naïve T cells into a population of heterogeneous effector T cells, and has been found to promote proliferation and survival of CD8 T cells. Thus, OX40 and it's ligand, OX40L, is a key player in pathways involving the immune system such as long-term T-cell immunity.

Research Area

Immunology & Inflammation

Images & Validation

• Tested Applications: ELISA, IHC
• Reactivity: Human
• Application Notes:
  1:50-1:200

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Monoclonal
• Isotype: IgG
• Clone No.: BKJE386
• Immunogen: Recombinant Protein
• Purity: Purified
• Purification: Purified
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: Tris Buffer, pH 7.3 - 7.7, with 1% rAlbumin and <0.1% Sodium Azide
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only