Nectin-4 Antibody (MMAE)

SKU: orb1805477

Description

Anti-Nectin-4 Reference Antibodyd antibody and Monomethyl auristatin E (MMAE) , suitable for adult patients with locally advanced or metastatic urothelial carcinoma, or who have received programmed cell death protein 1 (PD-1) inhibitor or programmed cell death ligand 1 (PD-L1) inhibitor therapy or neoadjuvant/adjuvant platinum-based chemotherapy for locally advanced or metastatic cancer.

Images & Validation

• Tested Applications: ELISA, FA, FACS, In vivo
• Reactivity: Human

Key Properties

• Antibody Type: Recombinant Antibody
• Clonality: Recombinant
• Target: Nectin-4
• Source/Expression System: CHO
• Molecular Weight: 143.9 kDa
• Purity: >95%
• Purification: Protein A
• Endotoxin: <0.001 EU/ug

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 100 mM Proline/Acetic acid 20mM Arginine pH 5.0
• Concentration: Batch dependent
• Disclaimer: For research use only

Anti-Nectin-4 Reference Antibody (enfortumab vedotin-ejfv) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

The purity of Anti-Nectin-4 Reference Antibody (enfortumab vedotin-ejfv)is more than 100% ;determined by SEC-HPLC.

Immobilized human NECTIN 4 His at 2 μg/mL can bind Anti-Nectin-4 Reference Antibody (enfortumab vedotin-ejfv);EC50=0.003846μg/mL.

Quick Database Links

Gene Symbol

Nectin-4

UniProt

Q96NY8