Anti-Nav1.1 Antibody

• Catalog Number: orb214555
• Category: Antibodies
• Description: Rabbit polyclonal antibody to SCN1A
• Target: SCN1A; SCN2A; SCN3A; SCN4A; SCN5A; SCN8A; SCN9A; SCN10A; SCN11A
• Clonality: Polyclonal
• Species/Host: Rabbit
• Conjugation: Unconjugated
• Reactivity: Human, Mouse, Rat
• Form/Appearance: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
• Buffer/Preservatives: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
• Purification: The antibody was purified by immunogen affinity chromatography.
• Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Nav1.1. The exact sequence is proprietary.
• UniProt ID: P35498, Q14524, Q99250, Q9NY46, Q9UI33, P04775, P35499, Q15858, P04774, P08104, P15390, Q9UQD0, Q9ER60, Q9Y5Y9
• Tested applications: IH, WB
• Dilution range: WB: 1-500-1-1000, IHC-P: 1-100-1-200
• Antibody Type: Primary Antibody
• Source: Rabbit
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Alternative names: Anti-brain sodium channel type I antibody, anti-EI
• Note: For research use only
• Entrez: 6335, 24766, 110880, 6326, 6323, 25722, 6328, 6334, 11280, 81574, 497770, 6336, 6329, 6331

Western blot analysis of Nav1.1 expression in SHSY5Y (A), mouse brain (B), PC12 (C) whole cell lysates. (Predicted band size: 227 kD; Observed band size: 230 kD)

Immunohistochemical analysis of Nav1.1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.