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Description
Research Area
Cell Biology, Immunology & Inflammation, Signal Transduction
Images & Validation
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Item 1 of 1
| Tested Applications | FC, ICC, IF, WB |
|---|---|
| Dilution Range | WB 1:500-2000 ICC/IF 1:50-200 FC 1:20 |
| Reactivity | Human |
Key Properties
−| Antibody Type | Primary Antibody |
|---|---|
| Host | Rabbit |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone No. | BCFFCX35 |
| Immunogen | A synthesized peptide derived from human MALT1 Enhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. Has ubiquitin ligase activity. MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion. |
| Target | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 |
| Molecular Weight | 40-48 kDa |
| Purification | Affinity-chromatography |
| Conjugation | Unconjugated |
Storage & Handling
−| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
|---|---|
| Form/Appearance | Liquid |
| Buffer/Preservatives | Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. *This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required. |
| Concentration | 0.5mg/ml |
| Expiration Date | 12 months from date of receipt. |
| Disclaimer | For research use only |
Alternative Names
−E3 ubiquitin-protein ligase NEDD4-like; 6.3.2.-; NEDD4.2; Nedd4-2; NEDD4L; KIAA0439, NEDL3
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Quick Database Links
Gene Symbol
Mucosa-associated lymphoid tissue lymphoma translocation protein 1
UniProt
UniProt Details
− No UniProt data available
Protocol Information
WB
Western Blot (IB, immunoblot)
FC
Flow Cytometry
IF
Immunofluorescence
ICC
Immunocytochemistry
Available Sizes
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Free Secondary Antibody (20 ul)0/0
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Usually dispatched within 2-4 weeks