Anti-Influenza agent 4

SKU: orb1745168

Description

Anti-Influenza agent 4 is a potent and selective small molecule inhibitor of influenza virus, demonstrating activity against A/Parma and A/Roma strains with EC50 values of 62 nM and 150 nM, respectively. This compound is a valuable research tool for studying influenza virus replication and pathogenesis in both in vitro and in vivo experimental models.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 522625-85-0
• MW: 386.42
• Purity: 99.86% (May vary between batches)
• Formula: C₁₉H₁₈N₂O₅S
• SMILES: S(NCC1=CC=CO1)(=O)(=O)C2=CC(NC(=O)C3=CC=C(OC)C=C3)=CC=C2
• Target: Influenza Virus
• Solubility: DMSO:45 mg/mL (116.45 mM)

Bioactivity

• Target IC50:
  A/Roma:150±0.07 nM|A/Roma:62±0.02 nM
• In Vitro:
  Anti influenza agent 4 (compound 5) (0-500 μM; 24 and 48 hours) showed low cytotoxicity in Madin-Darby canine kidney cells. In hemolytic inhibition assay anti influenza agent 4 showed an IC50 of 244 nM and 230.7 nM against influenza strains A/Roma and A/Parma, respectively.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Anti-Influenza agent 4, AntiInfluenzaagent4, Influenza Virus, Influenza virus, InfluenzaVirus

Compound Identifiers

PubChem CID

4156245