Anti-inflammatory agent 54

SKU: orb1944214

Description

Anti-inflammatory agent 54 (9c), a Coixol derivative, is a potent inhibitor of the NF-κB pathway. It suppresses pro-inflammatory mediators including iNOS, TNF-α, IL-6, and IL-1β, demonstrating in vitro activity in LPS-stimulated macrophages (IC50 = 2.4 μM) and in vivo efficacy in murine edema models.

Research Area

Cell Biology, Immunology & Inflammation, Signal Transduction

Key Properties

• CAS Number: 2924156-46-5
• MW: 328.32
• Formula: C₁₇H₁₆N₂O₅
• SMILES: C(CNC(/C=C/C1=CC=CO1)=O)N2C=3C(OC2=O)=CC(OC)=CC3
• Target: Interleukin,TNF,NO Synthase,Others,NF-κB

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

167437648