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Catalog Number | orb1173661 |
---|---|
Category | Antibodies |
Description | Anti-IL17RA (brodalumab biosimilar) mAb |
Target | IL17RA |
Clonality | Monoclonal |
Species/Host | Human |
Isotype | IgG2 |
Conjugation | Unconjugated |
Reactivity | Human |
Form/Appearance | Powder |
Purification | Purified from cell culture supernatant by affinity chromatography |
UniProt ID | Q96F46 |
Tested applications | ELISA, FC |
Dilution range | ELISA 1:5000-10000 Flow Cyt 1:100 |
Application notes | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Antibody Type | Biosimilar Antibody |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Alternative names | CD217CDw217IL-17RAIL17RCANDF5hIL-17R |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
ELISA plate pre-coated by 2 μg/ml (100 μL/well) Human IL17RA, His tagged protein orb689453 can bind Anti-IL17RA Neutralizing antibody (orb1173661) in a linear range of 3.2-80 ng/ml.
HEK293 cell line transfected with irrelevant protein (B) and human IL17RA (A) were surface stained with Anti-IL17RA mAb 1 μg/ml (brodalumab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.