Anti-IL-6 receptor [rhPM-1 (Tocilizumab)]

SKU: orb396139

Description

Mouse monoclonal antibody to IL-6 receptor.

Research Area

Immunology & Inflammation

Images & Validation

• Tested Applications: ELISA
• Reactivity: Human

Key Properties

• Host: Human
• Clonality: Monoclonal
• Isotype: IgG1
• Clone No.: rhPM-1 (Tocilizumab)
• Immunogen: The original antibody was generated by CDR grafting of mouse PM-1 antibody onto human REI and NEW framework regions to create rhPM-1.
• Target: IL-6 receptor
• Purity: Purified
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: PBS with 0.02% Proclin 300.
• Concentration: 1 mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

IL6R; IL-6R; CD126; MRA; atlizumab; TCZ; Interleukin-6 receptor subunit alpha; IL-6 receptor subunit alpha; IL-6R subunit alpha; IL-6R-alpha; IL-6RA; IL-6R 1; Membrane glycoprotein 80; gp80; PM1; PM-1

Quick Database Links

Gene Symbol

IL-6 receptor

UniProt

P08887

Sato, K. et al. Humanization of a mouse anti-human interleukin-6 receptor antibody comparing two methods for selecting human framework regions Mol Immunol, 31, 371-381 (1994)

PubMed: 8152440