SIGLEC10 Antibody

• Catalog Number: orb1729633
• Category: Antibodies
• Description: SIGLEC10 is a CD33-related receptor of sialoglycans, expressed on eosinophils, monocytes, a subpopulation of NK cells, and at lower level on B cells. Its murine ortholog is Siglec G. SIGLEC10 seems to act as an immunomodulatory receptor, which binds to VAP-1, a glycoprotein expressed on endothelium under inflammatory conditions. Another ligand of SIGLEC10 is CD24, a marker of poorer prognosis in carcinomas.
• Target: SIGLEC10
• Clonality: Monoclonal
• Isotype: Mouse IgG1
• Conjugation: Unconjugated
• Reactivity: Human
• Concentration: 1 mg/ml
• Buffer/Preservatives: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Purification: Purified by protein-A affinity chromatography.
• Immunogen: SIGLEC10 extracellular domain fused with human IgG1 Fc fragment
• UniProt ID: Q96LC7
• Tested applications: ELISA, IHC, IP
• Clone Number: 5G6
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Alternative names: PRO940, SGL2
• Note: For research use only
• Entrez: 89790

ELISA analysis of human SIGLEC 10-Fc fusion protein (5 μg/ml) using mouse monoclonal antibody 5G6 (0.016 - 10 μg/ml).