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Anti-Hu SIGLEC10 Purified
Catalog Number: orb1729633
| Catalog Number | orb1729633 |
|---|---|
| Category | Antibodies |
| Description | SIGLEC10 is a CD33-related receptor of sialoglycans, expressed on eosinophils, monocytes, a subpopulation of NK cells, and at lower level on B cells. Its murine ortholog is Siglec G. SIGLEC10 seems to act as an immunomodulatory receptor, which binds to VAP-1, a glycoprotein expressed on endothelium under inflammatory conditions. Another ligand of SIGLEC10 is CD24, a marker of poorer prognosis in carcinomas. |
| Clonality | Monoclonal |
| Clone Number | 5G6 |
| Tested applications | ELISA, IHC, IP |
| Reactivity | Human |
| Isotype | Mouse IgG1 |
| Immunogen | SIGLEC10 extracellular domain fused with human IgG1 Fc fragment |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Target | SIGLEC10 |
| Entrez | 89790 |
| UniProt ID | Q96LC7 |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Buffer/Preservatives | Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Alternative names | PRO940, SGL2 Read more... |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
ELISA analysis of human SIGLEC 10-Fc fusion protein (5 μg/ml) using mouse monoclonal antibody 5G6 (0.016 - 10 μg/ml).
