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Catalog Number | orb1729630 |
---|---|
Category | Antibodies |
Description | CD85g / ILT7 (immunoglobulin-like transcript 7) is a cell surface protein that is expressed on plasmacytoid dendritic cells (PDCs) and modulates the function of these cells in the immune response, such as the TLR-induced interferon production. It associates with gamma subunit of the high-affinity IgE receptor to form a receptor complex which transduces the signal through ITAM-associated downstream molecules. Expression of CD85g is downregulated by interleukin 3. |
Target | CD85g |
Clonality | Monoclonal |
Isotype | Mouse IgG1 kappa |
Conjugation | FITC |
Reactivity | Human |
Buffer/Preservatives | Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
UniProt ID | P59901 |
Tested applications | FC |
Application notes | Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. |
Clone Number | 17G10.2 |
Storage | Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze. |
Alternative names | ILT7, LILRA4 |
Note | For research use only |
Entrez | 23547 |
Expiration Date | 12 months from date of receipt. |
Separation of human CD123 positive CD85g positive leukocytes (red-filled) from neutrophil granulocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD85g (17G10.2) FITC antibody (4 μl reagent / 100 μl of peripheral whole blood).
Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD85g (17G10.2) FITC antibody (4 μl reagent / 100 μl of peripheral whole blood).