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Anti-Hu CD79a FITC

Catalog Number: orb1821019

DispatchUsually dispatched within 5-10 working days
$ 330.00
Catalog Numberorb1821019
CategoryAntibodies
DescriptionCD79a (Ig alpha, MB1) forms disulfide-linked heterodimer with CD79b (Ig beta). They both are transmembrane proteins with extended cytoplasmic domains containing immunoreceptor tyrosine activation motives (ITAMs), and together with cell surface immunoglobulin they constitute B-cell antigen-specific receptor (BCR). CD79a and b are the first components of BCR that are expressed developmentally. They appear on pro-B cells in association with the endoplasmic reticulum chaperone calnexin. Subsequently, in pre-B cells, CD79 heterodimer is associated with lambda5-VpreB surrogate immunoglobulin and later with antigen-specific surface immunoglobulins. At the plasma cell stage, CD79a is present as an intracellular component. CD79a/b complex interacts with Src-family tyrosine kinase Lyn, which phosphorylates its cytoplasmic ITAM motives to form docking sites for downstream signaling.
ClonalityMonoclonal
Clone NumberHM47
Tested applicationsFC
ReactivityBovine, Canine, Equine, Gallus, Guinea pig, Human, Mouse, Porcine, Primate, Rabbit, Rat
IsotypeMouse IgG1 kappa
ImmunogenSynthetic peptide corresponding to C terminal amino acids 208-222 of human CD79a
ConjugationFITC
TargetCD79a
Entrez973
UniProt IDP11912
StorageStore at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Buffer/PreservativesStabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Alternative namesBCR alpha, Ig-alpha, MB-1, IGA
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NoteFor research use only
Application notesFlow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. Intracellular staining.
Expiration Date12 months from date of receipt.
Anti-Hu CD79a FITC

Flow cytometry multicolor intracellular staining pattern of human lymphocytes using anti-human CD79a (HM47) FITC antibody (4 μl reagent / 100 μl of peripheral whole blood) and anti-human CD19 (LT19) APC antibody (10 μl reagent / 100 μl of peripheral whole blood).

Anti-Hu CD79a FITC

Separation of human CD19 positive CD79a positive lymphocytes (red-filled) from neutrophil granulocytes (black-dashed) in flow cytometry analysis (intracellular staining) of human peripheral whole blood stained using anti-human CD79a (HM47) FITC antibody (4 μl reagent / 100 μl of peripheral whole blood).

Anti-Hu CD79a FITC

Flow cytometry intracellular staining pattern of human peripheral whole blood stained using anti-human CD79a (HM47) FITC antibody (4 μl reagent / 100 μl of peripheral whole blood).

  • Anti-Hu CD79a FITC [orb179902]

    FC

    Bovine, Equine, Gallus, Guinea pig, Human, Mouse, Opossum, Porcine, Rabbit, Rat

    Monoclonal

    FITC

    100 T