CD7 Antibody (Biotin)

• Catalog Number: orb2281310
• Category: Antibodies
• Description: CD7, also known as gp40, is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL). CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 co-stimulation can induce cytokine secretion and modulate cellular adhesion. A ligand of CD7, epithelial cell secreted protein K12, is produced in thymus to regulate thymocyte signaling and cytokine release. In lung microvascular endothelial cells CD7 serves as an IgM Fc receptor. Expression of CD7 is an important marker used in leukemia diagnostics.
• Target: CD7
• Clonality: Monoclonal
• Isotype: Mouse IgG1
• Conjugation: Biotin
• Reactivity: Human
• Concentration: 1 mg/ml
• Buffer/Preservatives: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Purification: Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.
• Immunogen: not available
• UniProt ID: P09564
• Tested applications: FC
• Application notes: Flow cytometry: Recommended dilution: 1-5 μg/ml.
• Clone Number: 124-1D1
• Storage: Store at 2-8°C. Do not freeze.
• Alternative names: GP40, TLA, TP41, LEU-9
• Note: For research use only
• Entrez: 924
• Expiration Date: 12 months from date of receipt.