CD63 Antibody (Biotin)

SKU: orb154462

Description

Mouse monoclonal antibody conjugated to Biotin which recognizes is a CD63 that is lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is observed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. CD63 is belongs to the TM4 superfamily of leukocyte glycoproteins. CD63 may participates in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome.

Research Area

Immunology & Inflammation

Images & Validation

• Tested Applications: FC, ICC, IHC-P, IP
• Reactivity: Human
• Application Notes:
  Flow cytometry: Recommended dilution: 1-3 μg/ml; positive material: activated platelets, neutrophils and basophils.

Key Properties

• Antibody Type: Primary Antibody
• Clonality: Monoclonal
• Isotype: Mouse IgG1
• Clone No.: MEM-259
• Immunogen: HPB-ALL T cell line
• Target: CD63
• Purification: Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.
• Conjugation: Biotin

Storage & Handling

• Storage: Store at 2-8°C. Do not freeze.
• Buffer/Preservatives: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Concentration: 1 mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

OMA81H, Granulophysin, Tetraspanin-30, Tspan-30, MLA1, ME491, LAMP-3, OMA81H, TSPAN30

Quick Database Links

Gene Symbol

CD63

UniProt

P08962

NCBI Gene ID

967