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| Catalog Number | orb154432 |
|---|---|
| Category | Antibodies |
| Description | Mouse monoclonal antibody conjugated to APC which recognizes CD58. It binding can enhance antigen-specific T cell activation. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. CD58 is a cell adhesion molecule which plays a critical role in facilitation of antigen specific recognition through interaction with CD2 on T lymphocytes. It is a member of the immunoglobulin superfamily of molecules. |
| Target | CD58 |
| Clonality | Monoclonal |
| Isotype | Mouse IgG1 |
| Conjugation | APC |
| Reactivity | Human, Porcine |
| Buffer/Preservatives | Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide |
| Purification | Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography. |
| Immunogen | NALM-6 human pre-B cell line |
| UniProt ID | P19256 |
| Tested applications | FC |
| Application notes | Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. |
| Antibody Type | Primary Antibody |
| Clone Number | MEM-63 |
| Storage | Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze. |
| Alternative names | LFA3, AG3 |
| Research Area | Epigenetics |
| Note | For research use only |
| Entrez | 965 |
| Expiration Date | 12 months from date of receipt. |

Flow cytometry analysis (surface staining) of human peripheral blood cells with anti-CD58 (MEM-63) APC.
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