CD58 Antibody (APC)

SKU: orb154432

Description

Mouse monoclonal antibody conjugated to APC which recognizes CD58. It binding can enhance antigen-specific T cell activation. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. CD58 is a cell adhesion molecule which plays a critical role in facilitation of antigen specific recognition through interaction with CD2 on T lymphocytes. It is a member of the immunoglobulin superfamily of molecules.

Research Area

Epigenetics

Images & Validation

• Tested Applications: FC
• Reactivity: Human, Porcine
• Application Notes:
  Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Key Properties

• Antibody Type: Primary Antibody
• Clonality: Monoclonal
• Isotype: Mouse IgG1
• Clone No.: MEM-63
• Immunogen: NALM-6 human pre-B cell line
• Target: CD58
• Purification: Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
• Conjugation: APC

Storage & Handling

• Storage: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
• Buffer/Preservatives: Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

LFA3, AG3

Flow cytometry analysis (surface staining) of human peripheral blood cells with anti-CD58 (MEM-63) APC.

Quick Database Links

Gene Symbol

CD58

UniProt

P19256

NCBI Gene ID

965