CD371 Antibody (PE)

• Catalog Number: orb2704156
• Category: Antibodies
• Description: CD371, also known as CLEC12A, is a 30 kDa type II transmembrane glycoprotein of the C-type lectin family. Several alternatively spliced isoforms have been described. Using ITIM in its cytoplasmic part, this receptor serves as a negative regulator of CD371-positive cells, mainly granulocytes and monocytes, and is involved in dendritic cell maturation. It is one of markers of myeloid cells, including acute myeloid leukemia.
• Target: CD371
• Clonality: Monoclonal
• Isotype: Mouse IgG2a
• Conjugation: PE
• Reactivity: Human
• Buffer/Preservatives: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
• Immunogen: 293T cells expressing human CD371-Flag
• UniProt ID: Q5QGZ9
• Tested applications: FC
• Application notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
• Clone Number: 50C1
• Storage: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
• Alternative names: CLEC12A, CLL1, MICL, DCAL-2
• Note: For research use only
• Entrez: 160364
• Expiration Date: 12 months from date of receipt.

Separation of human monocytes (red-filled) from lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD371 (50C1) PE antibody (concentration in sample 0.56 µg/ml).

Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD371 (50C1) PE antibody (concentration in sample 0.56 µg/ml).