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| Catalog Number | orb2321160 |
|---|---|
| Category | Antibodies |
| Description | CD329 is a type I transmembrane glycoprotein of siglec family, which contains intracellular ITIM motif, and a SLAM-like motif, that acts as a docking site for SAP. CD329 can regulate TCR signaling by recruitment of SHP-1, which results in down-regulation of TCR-based gene transcription. It is expressed above all on monocytes, neutrophils, and a minor population of CD16+CD56- cells, weaker expression is detectable in some B cells, NK cells, and T cells. |
| Target | CD329 |
| Clonality | Monoclonal |
| Isotype | Mouse IgG1 kappa |
| Conjugation | APC |
| Reactivity | Human |
| Buffer/Preservatives | Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Purification | Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography. |
| Immunogen | recombinant CD329-Hu IgGFc fusion protein |
| UniProt ID | Q9Y336 |
| Tested applications | FC |
| Application notes | Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. |
| Clone Number | K8 |
| Storage | Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze. |
| Alternative names | SIGLEC9 |
| Note | For research use only |
| Entrez | 27180 |
| Expiration Date | 12 months from date of receipt. |

Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD329 (K8) APC antibody (10 μl reagent / 100 μl of peripheral whole blood).

Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD329 (K8) APC antibody (10 μl reagent / 100 μl of peripheral whole blood).
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