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| Catalog Number | orb154439 |
|---|---|
| Category | Antibodies |
| Description | Mouse monoclonal antibody conjugated to APC which recognizes CD180 that belongs to the toll-like receptor family. It is expressed on mature B cells, monocytes/macrophages and dendritic cells. CD180 is a signal transduction molecule and plays a role in regulation of B cell growth and death and also play a role in the innate immune response to bacterial lipopolysaccharide, through co-operation with MD-1 and TLR4. |
| Target | CD180 |
| Clonality | Monoclonal |
| Isotype | Mouse IgG1 kappa |
| Conjugation | APC |
| Reactivity | Human |
| Buffer/Preservatives | Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Purification | Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography. |
| Immunogen | Human tonsillar B cells |
| UniProt ID | Q99467 |
| Tested applications | FC |
| Application notes | Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. |
| Antibody Type | Primary Antibody |
| Clone Number | G28-8 |
| Storage | Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze. |
| Alternative names | LY64, Ly78, RP105, Bgp95 |
| Research Area | Epigenetics, Immunology |
| Note | For research use only |
| Entrez | 4064 |
| Expiration Date | 12 months from date of receipt. |

Flow cytometry analysis (surface staining) of human peripheral blood cells with anti-CD180 (G28-8) APC.
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