GUCY2C Biosimilar Antibody

• Catalog Number: orb1173635
• Category: Antibodies
• Description: Anti-GUCY2C(indusatumab biosimilar) mAb
• Target: GUCY2C
• Clonality: Monoclonal
• Species/Host: Human
• Isotype: IgG1
• Conjugation: Unconjugated
• Reactivity: Human
• Form/Appearance: Powder
• Purification: Purified from cell culture supernatant by affinity chromatography
• UniProt ID: P25092
• Tested applications: ELISA, FC
• Dilution range: ELISA 1:5000-10000 Flow Cyt 1:100
• Application notes: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
• Antibody Type: Biosimilar Antibody
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Alternative names: DIAR6GC-CGUC2CMECILMUCILSTAR
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

ELISA plate pre-coated by 1 μg/mL (100 μL/well) Human GUCY2C protein, His Tag orb1173928 can bind Anti-GUCY2C Neutralizing antibody (orb1173635) in a linear range of 3.2-400 ng/ml.

Flow cytometry analysis with Anti-GUCY2C (indusatumab biosimilar) mAb 1 μg/mL on Expi293 cells transfected with Human GUCY2C (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

Flow cytometry analysis of antigen binding of anti-human GUCY2C mAb (orb1173635). (A) orb1173635 does not bind to 293T cells that do not express GUCY2C. (B) A clear peak shift of orb1173635 was seen compared to the control when incubated with GUCY2C-expressing HT55 cells, indicating strong binding of orb1173635 to GUCY2C. Antibodies were incubated at 2 μg/mL.