Anti-FADD Monoclonal Antibody

• Catalog Number: orb547181
• Category: Antibodies
• Description: Anti-FADD Monoclonal Antibody
• Species/Host: Rabbit
• Clonality: Monoclonal
• Clone Number: ADDE-6
• Tested applications: FC, IHC, WB
• Reactivity: Mouse
• Isotype: Rabbit IgG
• Immunogen: A synthesized peptide derived from human FADD Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.
• Antibody Type: Primary Antibody
• Concentration: Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
• Form/Appearance: Liquid
• Conjugation: Unconjugated
• MW: 100-110 kDa
• UniProt ID: Q61160
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Alternative names: Peroxisome proliferator-activated receptor gamma c
• Note: For research use only
• Application notes: WB 1:500-1:2000IHC 1:50-1:200FC 1:50. Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
• Expiration Date: 12 months from date of receipt.

WB analysis of Fadd expression in Raw264.7 Cell using anti-Fadd antibody.