Drebrin Antibody

SKU: orb154400

Description

Mouse monoclonal antibody to Drebrin which developmentally regulated brain proteins highly expressed in brain neurons. It might play some role in cell migration, extension of neuronal processes and plasticity of dendrites, respectively. Decreases in Drebrin levels in the brain are associated with Alzheimers disease and Down syndrome.

Research Area

Alzheimer's, Developmental Biology, Epigenetics, Neuroscience, Signaling Pathways

Images & Validation

• Tested Applications: FC, WB
• Reactivity: Human
• Application Notes:
  Western blotting: Positive control: REH, Nalm-6, HEK293 cells. Flow cytometry: Recommended dilution: 1-4 µg/ml. Intracellular staining.

Key Properties

• Antibody Type: Primary Antibody
• Clonality: Monoclonal
• Isotype: Mouse IgG2b
• Clone No.: DBN-N-03
• Immunogen: Bacterially expressed N-terminal fragment of recombinant human drebrin (aa 1-326)
• Target: Drebrin
• Purification: Purified by protein-A affinity chromatography.
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
• Concentration: 1 mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

DBN, D0S117E

Quick Database Links

Gene Symbol

Drebrin

UniProt

Q16643

NCBI Gene ID

1627