DDX58 Rabbit Monoclonal Antibody

SKU: orb547186

Description

Anti-DDX58 Monoclonal Antibody. Tested in WB, IP applications. This antibody reacts with Human.

Research Area

Epigenetics & Chromatin, Immunology & Inflammation, Infectious Disease & Virology, Molecular Biology

Images & Validation

• Tested Applications: IP, WB
• Dilution Range: WB 1:500-2000 IP 1:50
• Reactivity: Human

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Monoclonal
• Isotype: Rabbit IgG
• Clone No.: ACEA-4
• Immunogen: A synthesized peptide derived from human DDX58 Retinoic acid inducible gene I (RIG-I) is a 925 amino acid, interferon-inducible cellular DExD/H box RNA helicase that activates type I interferon (IFN), an important effector of the innate immune system that is sensitive to these dsRNA viruses. dsRNA is normally present in very low quantities in cells, so when a virus is present, the elevated levels of dsRNA act as a sign telling RIG-I to activate the production of IFN.
• Target: Antiviral innate immune response receptor RIG-I
• Molecular Weight: 100-110 kDa
• Purification: Affinity-chromatography
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. *This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.
• Concentration: 0.5mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Histone H2AX; H2a/x; Histone H2A.X; H2AFX; H2AX

WB analysis of DDX58 expression in Jurkat Cell using anti-DDX58 antibody.

Quick Database Links

Gene Symbol

Antiviral innate immune response receptor RIG-I

UniProt

O95786