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Anti-Cytochrome P450 3A4 CYP3A4 Monoclonal Antibody
Catalog Number: orb547256
| Catalog Number | orb547256 |
|---|---|
| Category | Antibodies |
| Description | Anti-Cytochrome P450 3A4 CYP3A4 Monoclonal Antibody |
| Species/Host | Rabbit |
| Clonality | Monoclonal |
| Clone Number | ACDE-3 |
| Tested applications | IHC, IP, WB |
| Reactivity | Human |
| Isotype | Rabbit IgG |
| Immunogen | A synthesized peptide derived from human Cytochrome P450 3A4 Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. The enzyme also hydroxylates etoposide. |
| Antibody Type | Primary Antibody |
| Concentration | Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
| Form/Appearance | Liquid |
| Conjugation | Unconjugated |
| MW | 32 kDa |
| UniProt ID | P08684 |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Alternative names | Bone morphogenetic protein 2; BMP-2; Bone morphoge Read more... |
| Note | For research use only |
| Application notes | WB 1:1000-1:5000IHC 1:50-1:200IP 1:50. Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL |
| Expiration Date | 12 months from date of receipt. |
WB analysis of CYP3A4 using anti-CYP3A4 antibody in Human fetal liver lysate.
