CTLA-4 Biosimilar Antibody

SKU: orb689327

Description

Anti-CTLA4 (ipilimumab biosimilar) mAb

Images & Validation

• Tested Applications: ELISA, FC
• Dilution range: ELISA 1:5000-10000 Flow Cyt 1:100
• Reactivity: Human
• Application Notes:
  Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Key Properties

• Antibody Type: Biosimilar Antibody
• Host: Human
• Clonality: Monoclonal
• Isotype: IgG1
• Target: CTLA-4
• Purification: Purified from cell culture supernatant by affinity chromatography

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Powder
• Disclaimer: For research use only

Alternative Names

CTLA4CD152

ELISA plate pre-coated by 2 μg/ml (100 μL/well) Human CTLA4, mFc-His tagged protein ([getskuurl sku"orb689378"]) can bind Anti-CTLA4 Neutralizing antibody in a linear range of 0.13-16.0 ng/ml.

ELISA plate pre-coated by 2 μg/ml (100 μL/well) Human CTLA4, hFc tagged protein (orb689463) can bind Anti-CTLA4 Neutralizing antibody in a linear range of 0.64-80.0 ng/ml. In order to specifically detect orb689327, mouse anti-human Fab-specific antibody was used as detection antibody.

HEK293 cell line transfected with irrelevant protein (B) and human CTLA4 (A) were surface stained with anti-CTLA4 neutralizing antibody 1 μg/ml (ipilimumab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.

Quick Database Links

Gene Symbol

CTLA-4

UniProt

P16410