CEACAM6 Biosimilar Antibody

• Catalog Number: orb1291220
• Category: Antibodies
• Description: Anti-CEACAM6(tinurilimab biosimilar) mAb
• Target: CEACAM6
• Clonality: Monoclonal
• Species/Host: Human Humanized
• Isotype: IgG2
• Conjugation: Unconjugated
• Reactivity: Human
• Form/Appearance: Powder
• Purification: Purified from cell culture supernatant by affinity chromatography
• UniProt ID: P40199
• Tested applications: ELISA, FC
• Dilution range: ELISA 1:5000-10000 Flow Cyt 1:100
• Application notes: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
• Antibody Type: Biosimilar Antibody
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Alternative names: CD66cCEALNCA
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human CEACAM6 Protein, His Tag orb1173762 can bind Anti-CEACAM6 Neutralizing antibody (orb1291220) in a linear range of 0.61–156.25 ng/ml.

Flow cytometry analysis with 1 μg/mL Anti-CEACAM6 (tinurilimab biosimilar) mAb (orb1291220) on Expi293 cells transfected with Human CEACAM6 protein (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

Flow cytometry analysis of antigen binding of anti-human CEACAM6 mAb (orb1291220). (A) orb1291220 does not bind to Jurkat cells that do not express CEACAM6. (B) A clear peak shift of orb1291220 was seen compared to the control when incubated with CEACAM6-expressing TT cells, indicating strong binding of orb1291220 to CEACAM6. Antibodies were incubated at 5 μg/mL.