CEACAM5 Biosimilar Antibody

• Catalog Number: orb1173664
• Category: Antibodies
• Description: Anti-CEACAM5 (labetuzumab biosimilar) mAb
• Target: CEACAM5
• Clonality: Monoclonal
• Species/Host: Human Humanized
• Isotype: IgG1
• Conjugation: Unconjugated
• Reactivity: Human
• Form/Appearance: Powder
• Purification: Purified from cell culture supernatant by affinity chromatography
• UniProt ID: P06731
• Tested applications: ELISA, FC
• Dilution range: ELISA 1:5000-10000
• Application notes: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
• Antibody Type: Biosimilar Antibody
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Alternative names: CEACAM-5CD66eCEAMeconium antigen 100
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

ELISA plate pre-coated by 2 μg/ml (100 μL/well) Human CEACAM5, His tagged protein orb689419 can bind Anti-CEACAM5 Neutralizing antibody (orb1173664) in a linear range of 2.56-320 ng/ml.

Flow cytometry analysis with Anti-CEACAM5 (labetuzumab) on Expi293 cells transfected with human CEACAM5 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

Flow cytometry analysis of antigen binding of anti-human CEACAM5 mAb (orb1173664). (A) A clear peak shift of orb1173664 was seen compared to the control when incubated with CEACAM5-expressing MKN45 cells, indicating strong binding of orb1173664 to CEACAM5. Antibodies were incubated at 2 μg/mL.