CD33 Biosimilar Antibody

SKU: orb689320

Description

Anti-CD33 (gemtuzumab biosimilar) mAb

Images & Validation

• Tested Applications: FC
• Dilution range: Flow Cyt 1:100
• Reactivity: Human
• Application Notes:
  Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Key Properties

• Antibody Type: Biosimilar Antibody
• Host: Human Humanized
• Clonality: Monoclonal
• Isotype: IgG4
• Target: CD33
• Purification: Purified from cell culture supernatant by affinity chromatography

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Powder
• Disclaimer: For research use only

Alternative Names

CD33SIGLEC3gp67

HEK293 cell line transfected with irrelevant protein (B) and human CD33 (A) were surface stained with anti-CD33 neutralizing antibody 1 μg/ml (gemtuzumab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.

Flow cytometry analysis of antigen binding of anti-human CD33 mAb (orb689320). (A) A clear peak shift of orb689320 was seen compared to the control when incubated with CD33-expressing 8226 cells, indicating strong binding of orb689320 to CD33. Antibodies were incubated at 2 μg/mL.

Quick Database Links

Gene Symbol

CD33

UniProt

P20138