Anti-CD154 [IDEC-131 (Toralizumab)]

SKU: orb758972

Description

Mouse monoclonal antibody to CD154

Research Area

Cancer Biology, Immunology & Inflammation

Images & Validation

• Tested Applications: Blocking, IF
• Reactivity: Human

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: Mouse IgG1
• Clone No.: IDEC-131 (Toralizumab)
• Immunogen: The original monoclonal antibody was generated by immunization with a soluble fusion protein of human gp39 (gp39-CD8).
• Target: CD154
• Purity: Purified
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: PBS with 0.02% Proclin 300.
• Concentration: 1 mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CD40L; gp39; TRAP; Tumor necrosis factor ligand superfamily member 5; TNFSF5; T-cell antigen Gp39; TNF-related activation protein; TNF-related activation protein

Immunofluorescence staining of fixed Jurkat cells with anti-CD154 antibody IDEC-131 (Toralizumab). Immunofluorescence analysis of paraformaldehyde fixed Jurkat cells on Shi-fix™ coverslips stained with the chimeric rabbit IgG version of IDEC-131 (Toralizumab) (orb758973) at 10 µg/ml for 1h followed by Alexa Fluor® 488 secondary antibody (2 µg/ml), showing membrane staining. The nuclear stain is DAPI (blue). Panels show from left-right, top-bottom orb758973, DAPI, merged channels and an isotype control. The isotype control was an unknown specificity antibody (orb256458) followed by staining with Alexa Fluor® 488 secondary antibody.

Quick Database Links

Gene Symbol

CD154

UniProt

P29965