CCN2/CTGF Antibody

SKU: orb1806364

Description

Anti-CCN2 / CTGF Reference Antibody is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.

Images & Validation

• Tested Applications: ELISA, FA, FACS, In vivo
• Reactivity: Human

Key Properties

• Clonality: Monoclonal
• Target: CCN2 / CTGF
• Source/Expression System: CHO
• Molecular Weight: 144.86 kDa
• Purity: >95%
• Purification: Protein A
• Endotoxin: <0.001 EU/ug
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 100 mM Proline/Acetic acid 20mM Arginine pH 5.0
• Concentration: Batch dependent
• Disclaimer: For research use only

Anti-CCN2 / CTGF Reference Antibody (pamrevlumab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

The purity of Anti-CCN2 / CTGF Reference Antibody (pamrevlumab)is more than 100% ;determined by SEC-HPLC.

Immobilized human CTGF His at 2 μg/mL can bind Anti-CCN2 / CTGF Reference Antibody (pamrevlumab);EC50=0.006105 μg/mL.

Pamrevlumab inhibited the tumor growth of COLO205 on Balb/c nude mice. The result showed significant anti-tumor effects; with an tumor inhibition rate (TGI) of 39% at 40 mpk at D31.

Quick Database Links

Gene Symbol

CCN2 / CTGF

UniProt

P29279