Anti-CCN2 / CTGF Reference Antibody

• Catalog Number: orb1806364
• Category: Antibodies
• Description: Anti-CCN2 / CTGF Reference Antibody is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.
• Clonality: Monoclonal
• Tested applications: ELISA, FA, FACS, Kinetics
• Reactivity: Human
• Isotype: IgG
• Purity: > 95%
• Conjugation: Unconjugated
• MW: 150 kDa
• Target: CCN2 / CTGF
• Endotoxins: < 1 EU/mg
• Storage: -80°C
• Buffer/Preservatives: 100 mM Pro-Ac 20 mM Arg pH 5.0
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Anti-CCN2 / CTGF Reference Antibody (pamrevlumab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

The purity of Anti-CCN2 / CTGF Reference Antibody (pamrevlumab)is more than 100% ;determined by SEC-HPLC.

Immobilized human CTGF His at 2 μg/mL can bind Anti-CCN2 / CTGF Reference Antibody (pamrevlumab);EC50=0.006105 μg/mL.

Pamrevlumab inhibited the tumor growth of COLO205 on Balb/c nude mice. The result showed significant anti-tumor effects; with an tumor inhibition rate (TGI) of 39% at 40 mpk at D31.