Anti-ACVR2B(bimagrumab biosimilar) mAb

• Catalog Number: orb2321950
• Category: Antibodies
• Description: Anti-ACVR2B(bimagrumab biosimilar) mAb
• Species/Host: Human
• Clonality: Monoclonal
• Tested applications: ELISA, FC
• Reactivity: Human
• Isotype: IgG1(K97R,L117A,L118A)
• Antibody Type: Biosimilar Antibody
• Dilution range: ELISA 1:5000-10000, Flow Cyt 1:100
• Conjugation: Unconjugated
• Target: ACVR2B
• UniProt ID: Q13705
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Alternative names: AVR2B; ACTR-IIB
• Note: For research use only
• Application notes: Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
• Expiration Date: 12 months from date of receipt.

Flow cytometry analysis with 15 μg/mL Anti-ACVR2B (bimagrumab biosimilar) mAb (orb2321950) on Expi293 cells transfected with Human ACVR2B protein (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

Flow cytometry analysis with 1 μg/mL Anti-ACVR2B (bimagrumab biosimilar) mAb (orb2321950) on Expi293 cells transfected with Human ACVR2A protein (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human ACVR2B Protein, hFc Tag (orb2321328) can bind Anti-ACVR2B (bimagrumab biosimilar) mAb (orb2321950) in a linear range of 0.64–80 ng/ml.In order to specifically detect orb2321950, mouse anti-human Fab-specific antibody was used as detection antibody.