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Andrograpanin

SKU: orb1217626

Description

Andrograpanin is a bioactive compound from Andrographis paniculata. Andrograpanin has anti-inflammatory and anti-infectious properties.

Images & Validation

Key Properties

CAS Number82209-74-3
MW318.45
Purity>98% (HPLC)
FormulaC20H30O3
SMILESC[C@@](CO)(CCC1)[C@@H](CC2)[C@]1(C)[C@H](CCC1=CCOC1=O)C2=C
Targetp38 MAPK
SolubilityIn Vitro: DMSO : 100 mg/mL (314.02 mM)

Bioactivity

In Vitro
Andrograpanin exhibits anti-inflammatory properties in lipopolysaccharide-induced macrophage cells through down-regulating the p38 MAPKs signaling pathways. Andrograpanin enhances chemokine SDF-1α-induced leukocytes chemotaxis in Jurkat, THP-1 and PBL cells.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE

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Protocol Information

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5 mg
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