Amyloid Precursor Protein (APP), Peptide #3 Antibody

SKU: orb3167134

Description

This antibody recognizes the peptide sequence QHF QEK VES LEQ EAA NER AA, which corresponds to residues #433-452 of the human APP gene product. This peptide sequence is 100% conserved between human, mouse and rat homologs of APP, and the antibodies against this sequence cross-react with all three species. The antibody preparation is at a concentration of 100 µg/mL (based on absorbance at 280 nm).

Images & Validation

• Tested Applications: ICC, IHC
• Dilution Range: IHC: 1:500-1:1000; ICC: 1:500-1:1000
• Reactivity: Human, Mouse, Rat

Key Properties

• Host: Gallus
• Clonality: Polyclonal
• Isotype: IgY
• Immunogen: Synthetic peptide (QHF QEK VES LEQ EAA NER AA, residues #433-452) from the human APP gene product
• Target: Amyloid Precursor Protein (APP), Peptide #3
• Molecular Weight: 87 kDa
• Purification: Affinity-Purified IgY
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: Phosphate-buffered (10 mM) isotonic (0.9%, w/v) saline (“PBS," pH 7.2) with sodium azide (0.02%, w/v) added as a preservative.
• Concentration: 100 µg/mL
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Amyloid-beta A4 protein (ABPP) (APPI) (Alzheimer disease amyloid protein) (Amyloid precursor protein) (Amyloid-beta precursor protein) (Cerebral vascular amyloid peptide) (CVAP) (PreA4) (Protease nexin-II) (PN-II) [Cleaved into: N-APP; Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (Beta-secretase C-terminal fragment) (Beta-CTF); Amyloid-beta protein 42 (Abeta42) (Beta-APP42); Amyloid-beta protein 40 (Abeta40) (Beta-APP40); C83 (Alpha-secretase C-terminal fragment) (Alpha-CTF); P3(42); P3(40); C80; Gamma-secretase C-terminal fragment 59 (Amyloid intracellular domain 59) (AICD-59) (AID(59)) (Gamma-CTF(59)); Gamma-secretase C-terminal fragment 57 (Amyloid intracellular domain 57) (AICD-57) (AID(57)) (Gamma-CTF(57)); Gamma-secretase C-terminal fragment 50 (Amyloid intracellular domain 50) (AICD-50) (AID(50)) (Gamma-CTF(50)); C31]

Quick Database Links

Gene Symbol

Amyloid Precursor Protein (APP), Peptide #3

UniProt

P05067