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| Catalog Number | orb1727738 |
|---|---|
| Category | Antibodies |
| Description | AMP-activated protein kinase (AMPK) is highly conserved from yeast to plants and animals and plays a key role in the regulation of energy homeostasis. Accumulating evidence indicates that AMPK not only regulates the metabolism of fatty acids and glycogen, but also modulates protein synthesis and cell growth through EF2 and TSC2/mTOR pathways, as well as blood flow via eNOS/nNOS. |
| Clonality | Recombinant |
| Species/Host | Rabbit |
| Isotype | Rabbit IgG |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Form/Appearance | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification | Affinity-chromatography |
| Immunogen | A synthesized peptide derived from human AMPK alpha 1 |
| UniProt ID | Q13131 |
| MW | 64kDa |
| Tested applications | ICC, IP, WB |
| Dilution range | WB:1:1000~1:2000ICC/IF:1:50~1:200IP:1:50 |
| Antibody Type | Recombinant Antibody |
| Source | Recombinant Rabbit |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Alternative names | 5'-AMP-activated protein kinase catalytic subunit Read more... |
| Note | For research use only |
![AMPK alpha 1 (Phospho-Ser496) Rabbit mAb [KD Validated]](/images/pub/media/catalog/product/NewWebsite/18/orb1727738_1.png)
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
![AMPK alpha 1 (Phospho-Ser496) Rabbit mAb [KD Validated]](/images/pub/media/catalog/product/NewWebsite/18/orb1727738_2.png)
Western blot analysis of Phospho-AMPK alpha 1 (S496) expression in (1) 293T cell lysate treated with LP; (2) 293T cell lysate.
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