Amlodipine

SKU: orb1308773

Description

Amlodipine

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 88150-42-9
• MW: 408.88
• Purity: 99.85%
• Formula: C₂₀H₂₅ClN₂O₅
• SMILES: OS(=O)(=O)C1=CC=CC=C1.CCOC(=O)C1=C(COCCN)NC(C)=C(C1C1=CC=CC=C1Cl)C(=O)OC
• Target: Calcium Channel
• Solubility: DMSO:90 mg/mL (220.11 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (6.11 mM);Ethanol:76 mg/mL (185.87 mM)

Bioactivity

• In Vivo:
  In large coronary arteries and aorta, Amlodipine increased nitrite production. Intracellularly, Amlodipine caused neuronal Ca2+ elevation by attenuating KCl depolarization.
• In Vitro:
  In large coronary arteries and aorta, Amlodipine increased nitrite production. Intracellularly, Amlodipine caused neuronal Ca2+ elevation by attenuating KCl depolarization.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CalciumChannel, dihydropyridine, Ca2+ channels, Ca channels, Calcium Channel, Amlodipine, antianginal, hypertension, Inhibitor, inhibit, oral, UK 48340, UK48340, UK-48340

Compound Identifiers

PubChem CID

60496