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Amlodipine

SKU: orb1308773

Description

Amlodipine

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number88150-42-9
MW408.88
Purity99.85%
FormulaC20H25ClN2O5
SMILESOS(=O)(=O)C1=CC=CC=C1.CCOC(=O)C1=C(COCCN)NC(C)=C(C1C1=CC=CC=C1Cl)C(=O)OC
TargetCalcium Channel
SolubilityDMSO:90 mg/mL (220.11 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (6.11 mM);Ethanol:76 mg/mL (185.87 mM)

Bioactivity

In Vivo
In large coronary arteries and aorta, Amlodipine increased nitrite production. Intracellularly, Amlodipine caused neuronal Ca2+ elevation by attenuating KCl depolarization.
In Vitro
In large coronary arteries and aorta, Amlodipine increased nitrite production. Intracellularly, Amlodipine caused neuronal Ca2+ elevation by attenuating KCl depolarization.

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
DisclaimerFor research use only

Alternative Names

CalciumChannel, dihydropyridine, Ca2+ channels, Ca channels, Calcium Channel, Amlodipine, antianginal, hypertension, Inhibitor, inhibit, oral, UK 48340, UK48340, UK-48340

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Key Properties

No computed properties available.

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Amlodipine (orb1308773)

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% Tween 80 +
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