Amlodipine

SKU: orb1308773

Description

Amlodipine

Research Area

Cell Biology, Neuroscience

Key Properties

• CAS Number: 88150-42-9
• MW: 408.9
• Purity: >98%
• Formula: C₂₀H₂₅ClN₂O₅
• SMILES: OS(=O)(=O)C1=CC=CC=C1.CCOC(=O)C1=C(COCCN)NC(C)=C(C1C1=CC=CC=C1Cl)C(=O)OC
• Target: Ion channel
• Solubility: Soluble in DMSO (up to 25 mg/ml), in DMF (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).

Bioactivity

• In Vivo:
  In large coronary arteries and aorta, Amlodipine increased nitrite production. Intracellularly, Amlodipine caused neuronal Ca2+ elevation by attenuating KCl depolarization.
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• In Vitro:
  In large coronary arteries and aorta, Amlodipine increased nitrite production. Intracellularly, Amlodipine caused neuronal Ca2+ elevation by attenuating KCl depolarization.
  Read more...

Storage & Handling

• Storage: RT
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CalciumChannel, dihydropyridine, Ca2+ channels, Ca channels, Calcium Channel, Amlodipine, antianginal, hypertension, Inhibitor, inhibit, oral, UK 48340, UK48340, UK-48340

Compound Identifiers

PubChem CID

60496