Levamlodipine besylate

SKU: orb1302988

Description

Levamlodipine besylate (CAS 103129-82-4 (free base)), the pharmacologically active S-enantiomer of amlodipine, is a dihydropyridine calcium channel blocker. It is widely used in research for investigating hypertension and angina mechanisms, with applications in both in vitro receptor binding studies and in vivo cardiovascular models.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 150566-71-5
• MW: 567.05
• Purity: 99.86%
• Formula: C₂₆H₃₁ClN₂O₈S
• SMILES: OS(=O)(=O)c1ccccc1.CCOC(=O)C1=C(COCCN)NC(C)=C([C@@H]1c1ccccc1Cl)C(=O)OC
• Target: Calcium Channel
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.53 mM);DMSO:60 mg/mL (105.81 mM)

Bioactivity

• Target IC50:
  Ca2+ channel:
• In Vitro:
  Amlodipine is a calcium channel blocker prescribed fo the management of angina and hypertension. As a racemic mixture, amlodipine contains (R)- and (S)-amlodipine isomers, but only (S)-amlodipine a the active moiety possesses therapeutic activity

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

(S)-Amlodipine besylate, (S)-Amlodipine Besylate (103129-82-4(free base)), Amlodipine Besylate (103129-82-4(free base)), Ca channels, Ca2+ channels, Calcium channel, Calcium Channel, CalciumChannel, Inhibitor, Levamlodipine besylate, Levoamlodipine besylate, inhibit

Compound Identifiers

PubChem CID

11365087