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Amifostine thiol

SKU: orb1692806

Description

Amifostine thiol

Research Area

Cell Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number31098-42-7
MW134.24
Purity≥95.0% (May vary between batches)
FormulaC5H14N2S
SMILESNCCCNCCS
Targetp53,Mdm2,MDM-2/p53
SolubilityH2O:80 mg/mL (595.95 mM);DMSO:200 mg/mL (1489.87 mM)

Bioactivity

In Vitro
4 mM Amifostine thiol exhibits a protective effect against the genome instability induced by 30 minutes of X-ray irradiation, and also protects RKO36 cells from chromosomal damage and death caused by ionizing radiation.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

WR-1065, MDM-2/p53, Amifostine thiol

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Key Properties

No computed properties available.

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Amifostine thiol (orb1692806)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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