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AMG-1

SKU: orb1741072

Description

AMG-1 is a selective CRAC channel inhibitor that suppresses effector T cell activity while sparing regulatory T cells in vitro. It has been shown to ameliorate disease progression in the EAE mouse model, making it a useful research tool for studying T cell-mediated autoimmunity and calcium signaling.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number903591-53-7
MW413.73
FormulaC18H9ClF5N3O
SMILESClC=1C(=CC(C(F)(F)F)=CC1)C=2C=NC(NC(=O)C3=C(F)C=CC=C3F)=CN2
TargetCalcium Channel,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information