Amcasertib

SKU: orb1303462

Description

Amcasertib (BBI503) is an oral small molecule inhibitor targeting stemness kinases to disrupt cancer stem cell pathways. It has demonstrated activity in preclinical in vitro and in vivo studies across various cancer types, including colon and breast cancer models, supporting its investigation as an anti-cancer stem cell therapeutic.

Research Area

Cell Biology, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 1129403-56-0
• MW: 539.69
• Purity: >99.99% (May vary between batches)
• Formula: C₃₁H₃₃N₅O₂S
• SMILES: CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2\C(=O)Nc3ccc(cc23)-c2csc(n2)-c2ccccc2)c1C
• Target: Apoptosis,Others,Stemness kinase
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.85 mM);DMSO:5.4 mg/mL (10.01 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

BBI 503, BBI503, BBI-503, Amcasertib, inhibit, Inhibitor, Stemness kinase, Stemnesskinase

Compound Identifiers

PubChem CID

122412734