Alpha2C Adrenergic Antibody (APC)

SKU: orb150421

Description

Mouse monoclonal to Alpha 2C Adrenergic R (APC). The alpha 2C Adrenergic Receptor controls the release of neurotransmitter from central adrenergic neurons and from sympathetic nerves in the heart. This receptor also plays a role in cognitive and behavioral function. Two variants are produced by alternative splicing. Alpha 2C Adrenergic Receptor has been reported extensively in the brain. Blood, corpus cavermosum, kidney, and heart tissues have also been reported to express the protein..

Research Area

Neuroscience, Signal Transduction

Images & Validation

• Tested Applications: ICC, IF, WB
• Dilution Range: WB (1:1000)
• Reactivity: Human, Mouse
• Application Notes:
  1 µg/ml was sufficient for detection of Alpha2C Adrenergic Receptor in 20 µg of COS cells transiently transfected with HA-tagged Alpha- lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Clone No.: N330A/80 (Formerly sold as S330A-80)
• Immunogen: Synthetic peptide amino acids 442- 462 (QDFRRSFKHILFRRRRRGFRQ, cytoplasmic C-terminus) of human Alpha-2C adrenergic receptor
• Target: Alpha2C Adrenergic
• Molecular Weight: 50kDa
• Purification: Protein G Purified
• Conjugation: APC

Storage & Handling

• Storage: Conjugated antibodies should be stored according to the product label
• Buffer/Preservatives: 95.46mM Phosphate, 2.48mM MES and 2mM EDTA
• Concentration: 1 mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Alpha-2C Adrenergic Receptor, Alpha-2C Adrenoceptor, Alpha-2C Adrenoreceptor, ADRA2C, ADRA2L2, ADRA2RL2, ADRARL2, ALPHA2CAR, Alpha2-AR-C4, Alpha2-C4, Adrenoceptor Alpha 2C, Adrenergic receptor alpha 2C

Quick Database Links

Gene Symbol

Alpha2C Adrenergic

UniProt

P18825

NCBI Gene ID

152

RefSeq (Protein):NP_000674.2