SERPINA1 Antibody

SKU: orb2309855

Description

SERPINA1 Antibody

Research Area

Cardiovascular Research, Immunology & Inflammation, Stem Cell & Developmental Biology

Images & Validation

• Tested Applications: IHC, WB
• Reactivity: Human

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Clone No.: AAT/4615
• Immunogen: Recombinant fragment (around aa200-400) of human SERPINA1 protein (exact sequence is proprietary)
• Target: SERPINA1
• Source/Expression System: Bioreactor
• Molecular Weight: 46kDa
• Purification: Protein G
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% rAlbumin & 0.05% azide. Also available WITHOUT rAlbumin & azide at 1.0mg/ml.
• Disclaimer: For research use only

Alternative Names

A1AT; Alpha-1 protease inhibitor; Alpha-1-antiproteinase (Alpha1AT); Dom1; Serine (or cysteine) proteinase inhibitor clade A member 1; Serpin peptidase inhibitor clade A member 1; Short peptide from AAT (SPAAT); Spi1-1

Analysis of Protein Array containing more than 19000 full-length human proteins using Alpha-1-Antitrypsin Mouse Monoclonal (AAT/4615). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Formalin-fixed, paraffin-embedded human liver stained with Alpha-1-Antitrypsin Mouse Monoclonal Antibody (AAT/4615). HIER: Tris/EDTA, pH9.0, 45 min. 2°C: HRP-polymer, 30 min. DAB, 5 min.

SDS-PAGE Analysis of Purified Alpha-1-Antitrypsin Mouse Monoclonal Antibody (AAT/4615). Confirmation of Purity and Integrity of Antibody.

Western blot analysis of human Lung tissue lysate using SERPINA1 Mouse Monoclonal Antibody (AAT/4615).

Western Blot Analysis of T47D cell lysate using AAT Mouse Monoclonal Antibody (AAT/4615).

Quick Database Links

Gene Symbol

SERPINA1

UniProt

P01009