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ALK inhibitor 2

SKU: orb1304599

Description

ALK inhibitor 2 is a novel, selective small molecule targeting the anaplastic lymphoma kinase (ALK). It is a valuable research tool for investigating ALK-driven pathologies, such as certain cancers, in both cellular (in vitro) and animal model (in vivo) studies.

Research Area

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number761438-38-4
MW518.03
Purity99.00% (May vary between batches)
FormulaC23H28ClN7O3S
SMILESCNS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(cc2OC)N2CCN(C)CC2)ncc1Cl
TargetFAK,ALK
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.93 mM);DMSO:5.19 mg/mL (10.02 mM)

Bioactivity

Target IC50
FAK:5 nM (IC50)|TSSK2:37 nM (IC50)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

TSSK2, testis-specific, PTK2, PTK2 protein tyrosine kinase 2, reversible, serine/threonine, kinase, inhibit, Inhibitor, male, FAK, focal, Focal adhesion kinase, ALK, ALK tyrosine kinase receptor, ALK inhibitor 2, ALK inhibitor2, ALK inhibitor-2, adhesion, Anaplastic lymphoma kinase (ALK), Anaplastic lymphoma kinase, contraception, Cluster of differentiation 246, CD246

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Key Properties

No computed properties available.

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Protocol Information

ALK inhibitor 2 (orb1304599)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 160.00
2 mg
$ 210.00
5 mg
$ 300.00
10 mg
$ 400.00
25 mg
$ 630.00
50 mg
$ 890.00
100 mg
$ 1,170.00
DispatchUsually dispatched within 3-5 working days
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