ALK inhibitor 2

SKU: orb1304599

Description

ALK inhibitor 2 is a novel, selective small molecule targeting the anaplastic lymphoma kinase (ALK). It is a valuable research tool for investigating ALK-driven pathologies, such as certain cancers, in both cellular (in vitro) and animal model (in vivo) studies.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 761438-38-4
• MW: 518.03
• Purity: >99.99% (May vary between batches)
• Formula: C₂₃H₂₈ClN₇O₃S
• SMILES: CNS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(cc2OC)N2CCN(C)CC2)ncc1Cl
• Target: FAK,ALK
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.93 mM);DMSO:5.19 mg/mL (10.02 mM)

Bioactivity

• Target IC50:
  FAK:5 nM (IC50)|TSSK2:37 nM (IC50)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

TSSK2, testis-specific, PTK2, PTK2 protein tyrosine kinase 2, reversible, serine/threonine, kinase, inhibit, Inhibitor, male, FAK, focal, Focal adhesion kinase, ALK, ALK tyrosine kinase receptor, ALK inhibitor 2, ALK inhibitor2, ALK inhibitor-2, adhesion, Anaplastic lymphoma kinase (ALK), Anaplastic lymphoma kinase, contraception, Cluster of differentiation 246, CD246

Compound Identifiers

PubChem CID

66577032