CEP-14083

SKU: orb1740942

Description

CEP-14083 is a potent, ATP-competitive ALK inhibitor with an IC50 of 11 nM, also active against the insulin receptor. It modulates T-cell identity signaling via NPM/ALK inhibition and has demonstrated preclinical efficacy in both cellular assays and animal models of ALK-altered lymphoma.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 856692-39-2
• MW: 518.61
• Formula: C₃₁H₃₀N₆O₂
• SMILES: C(CC)N1C=2C(=C3C(=C4C2CCC=5C4=CN(C)N5)C(=O)NC3)C=6C1=CC=C(NC(N(C)C7=CC=CC=C7)=O)C6
• Target: ALK,VEGFR,IGF-1R,Tie-2,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

44418327