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AG-825

SKU: orb2901636

Description

AG-825 (Tyrphostin AG-825) is a selective and ATP-competitive ErbB2 inhibitor which suppresses tyrosine phosphorylation, with an IC50 of 0.35 μM. AG-825 displays anti-cancer activity.AG825 significantly accelerates apoptosis of human neutrophils. AG-825 is a potential agent for overcoming Mn-induced neurotoxicity or AD development.

Images & Validation

Key Properties

CAS Number149092-50-2
MW397.47
Purity>98% (HPLC)
FormulaC19H15N3O3S2
SMILESCOc1cc(\C=C(/C#N)C(N)=O)cc(CSc2nc3ccccc3s2)c1O
TargetEGFR
SolubilityIn Vitro: DMSO : 250 mg/mL (628.98 mM; Ultrasonic )

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • AG-825 [orb1707709]

    99.52% (May vary between batches)

    149092-50-2

    397.47

    C19H15N3O3S2

    50 mg, 5 mg, 10 mg, 25 mg, 500 mg, 1 ml x 10 mM (in DMSO), 100 mg, 1 mg
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Protocol Information

AG-825 (orb2901636)

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Available Sizes

Select a size below

2 mg
$ 90.00
5 mg
$ 110.00
10 mg
$ 160.00
25 mg
$ 310.00
50 mg
$ 490.00
100 mg
$ 760.00
500 mg
$ 1,530.00