AFAP1 Antibody (C-term)

SKU: orb30773

Description

Rabbit polyclonal antibody to AFAP1 protein encoded by this gene is a Src binding partner. May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation. It may represent a potential modulator of actin filament integrity in response to cellular signals, and may function as an adaptor protein by linking Src family members and/or other signaling proteins to actin filaments. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Area

Signal Transduction

Images & Validation

• Tested Applications: WB
• Dilution Range: WB - 1:1000
• Reactivity: Human

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Clone No.: BTD54666
• Immunogen: Synthetic Peptide
• Target: AFAP1
• Molecular Weight: 80725
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
• Form/Appearance: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Anti-Actin filament-associated protein 1 antibody, anti-AFAP1 antibody, anti-AFAP antibody

AFAP1 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35 ug/lane). This demonstrates the AFAP1 antibody detected the AFAP1 protein (arrow).

Quick Database Links

Gene Symbol

AFAP1

UniProt

Q8N556

RefSeq (Protein):NP_001128119.1, NP_940997.1