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AEM1

SKU: orb1298474

Description

AEM1 is a small molecule inhibitor that suppresses oncogenic NRF2 signaling. It downregulates NRF2 target genes, enhancing chemosensitivity in A549 lung cancer cells and impeding tumor growth in both cell culture and animal models, supporting its use in cancer therapeutics research.

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

CAS Number1030123-90-0
MW379.407
Purity99.88% (May vary between batches)
FormulaC20H14FN3O2S
SMILESFC1=CC=C(C=C1)C1=CSC2=C1C(NCC1=CC=C3OCOC3=C1)=NC=N2
TargetNrf2
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.27 mM);DMSO:30 mg/mL (79.07 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

AEM 1, AEM1, AEM-1, Inhibitor, NRF2, Keap1-Nrf2, inhibit

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

2 mg
$ 70.00
5 mg
$ 90.00
1 ml x 10 mM (in DMSO)
$ 100.00
10 mg
$ 130.00
25 mg
$ 220.00
50 mg
$ 320.00
100 mg
$ 490.00
DispatchUsually dispatched within 5-10 working days
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