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AEM1

SKU: orb1219176

Description

AEM1 is an inhibitor of deregulated NRF2 transcriptional activity in cancer. AEM1 acts by broadly decreasing the expression of NRF2 controlled genes, sensitizing A549 cells to various chemotherapeutic agents, and inhibiting the growth of A549 cells in vitro and in vivo.

Images & Validation

Key Properties

CAS Number1030123-90-0
MW379.4
Purity>98% (HPLC)
FormulaC20H14FN3O2S
SMILESC1OC2=C(O1)C=C(C=C2)CNC3=C4C(=CSC4=NC=N3)C5=CC=C(C=C5)F
TargetKeap1-Nrf2
SolubilityDMSO:10 mM

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information

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500 mg
200 mg
5 mg
$ 90.00
10 mg
$ 150.00
25 mg
$ 290.00
50 mg
$ 500.00
100 mg
$ 840.00