Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

Ack1 inhibitor 1

SKU: orb2567084

Description

Ack1 inhibitor 1 is a potent, selective, and orally bioavailable small molecule targeting ACK1 kinase with an IC50 of 2.1 nM. It blocks ACK1 autophosphorylation and downstream AKT signaling, showing anti-proliferative effects in cellular assays and demonstrating in vivo efficacy in xenograft tumor models.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2924415-92-7
MW727.77
FormulaC39H40F3N7O4
SMILESC(N1C=2C(C=C(C1=O)C3=CC(NC(=O)C4=CC(C(F)(F)F)=CC=C4)=CC=C3)=CN=C(NC5=C(OCC)C=C(C=C5)N6CCN(C)CC6)N2)[C@H]7CCCO7
TargetAkt,ACK1

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Similar Products

  • KRCA-0008 [orb1305226]

    96.19%

    1472795-20-2

    609.12

    C30H37ClN8O4

    5 mg, 10 mg, 25 mg, 50 mg, 1 ml x 10 mM (in DMSO), 100 mg
  • AIM-100 [orb1302098]

    98.75%

    873305-35-2

    371.43

    C23H21N3O2

    25 mg, 50 mg, 10 mg, 100 mg, 1 ml x 10 mM (in DMSO), 5 mg, 2 mg
  • AZ7550 hydrochloride [orb1308863]

    99.65%

    2309762-40-9

    522.04

    C27H32ClN7O2

    1 mg, 5 mg, 10 mg, 25 mg, 50 mg
  • AZ7550 [orb1708049]

    99.75%

    1421373-99-0

    485.58

    C27H31N7O2

    25 mg, 1 mg, 5 mg, 10 mg, 50 mg, 100 mg
  • GNF-7 [orb1304437]

    99.70% (May vary between batches)

    839706-07-9

    547.53

    C28H24F3N7O2

    50 mg, 25 mg, 1 mg, 100 mg, 1 ml x 10 mM (in DMSO), 5 mg, 10 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

Ack1 inhibitor 1 (orb2567084)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%