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Ack1 inhibitor 1

SKU: orb2567084

Description

Ack1 inhibitor 1 is a potent, selective, and orally bioavailable small molecule targeting ACK1 kinase with an IC50 of 2.1 nM. It blocks ACK1 autophosphorylation and downstream AKT signaling, showing anti-proliferative effects in cellular assays and demonstrating in vivo efficacy in xenograft tumor models.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number2924415-92-7
MW727.77
FormulaC39H40F3N7O4
SMILESC(N1C=2C(C=C(C1=O)C3=CC(NC(=O)C4=CC(C(F)(F)F)=CC=C4)=CC=C3)=CN=C(NC5=C(OCC)C=C(C=C5)N6CCN(C)CC6)N2)[C@H]7CCCO7
TargetAkt,ACK1

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information