ACHE Antibody (N-term)

SKU: orb38623

Description

Rabbit polyclonal antibody to ACHE which is also known as acetylcholinesterase whose expression can be detected in the blood cells but it is majorly expressive in the erythrocytes. It is found in the post synapse. It performs several functions like protein self-association and serine hydrolase activity. It can terminate signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft and has a role in neuronal apoptosis.

Research Area

Signal Transduction

Images & Validation

• Tested Applications: FC, IF, IHC-P, WB
• Dilution Range: WB: 1:1000, IHC-P: 1:10-50, FACS: 1:10-50, IF/ICC: 1:10-50
• Reactivity: Human
• Predicted Reactivity: Guinea pig

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Immunogen: Synthetic Peptide
• Target: ACHE
• Molecular Weight: 67796
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
• Form/Appearance: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Anti-Acetylcholinesterase antibody, anti-AChE antibody, anti-ACHE antibody

Quick Database Links

Gene Symbol

ACHE

UniProt

P22303

RefSeq (Protein):NP_001269378.1, NP_056646.1, NP_000656.1

Mukhopadhyay, Bedabrata et al. Immunohistochemistry-based comparative study in detection of Hirschsprung's disease in infants in a Tertiary Care Center J Lab Physicians, 9, 76-80 (2017)

PubMed: 28367019

Bedabrata Mukhopadhyay, Moumita Sengupta, Chhanda Das, Madhumita Mukhopadhyay, Shibsankar Barman, Biswanath Mukhopadhyay Immunohistochemistry-based comparative study in detection of Hirschsprung’s disease in infants in a Tertiary Care Center Journal of Laboratory Physicians, 9, 76 (2017)

PubMed: 28367019

Applications

IHC

Reactivity

Human