Ac-FLTD-CMK

SKU: orb2901006

Description

Ac-FLTD-CMK, a gasdermin D (GSDMD)-derived inhibitor, is a specific inflammatory caspases inhibitor. Ac-FLTD-CMK is effective against caspases-1 (IC50 of 46.7 nM), caspases-4 (IC50 of 1.49 μM), caspases-5 (IC50 of 329 nM), and caspases-11 , but not the apoptotic caspases such as caspase-3.

Key Properties

• CAS Number: 2376255-48-8
• MW: 569.05
• Purity: >98% (HPLC)
• Formula: C₂₆H₃₇ClN₄O₈
• SMILES: CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)CCl
• Target: Caspase
• Solubility: In Vitro: DMSO : 100 mg/mL (175.73 mM; Ultrasonic )

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Caspase