AC-55541

SKU: orb1305582

Description

AC-55541 (AOB2796) is a potent and selective PAR2 agonist, demonstrating activity in cellular proliferation, phosphatidylinositol hydrolysis, and calcium mobilization assays with EC50 values of 200-1000 nM. This tool compound is used in vitro to study protease-activated receptor 2 signaling in inflammation, pain, and cancer research fields.

Research Area

Pharmacology & Drug Discovery, Protein Biochemistry

Key Properties

• CAS Number: 916170-19-9
• MW: 518.36
• Purity: 99.35%
• Formula: C₂₅H₂₀BrN₅O₃
• SMILES: C\C(=N/NC(=O)C(NC(=O)c1ccccc1)c1n[nH]c(=O)c2ccccc12)c1cccc(Br)c1
• Target: Protease-activated Receptor,Proteasome
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.93 mM);DMSO:5.19 mg/mL (10.01 mM)

Bioactivity

• Target IC50:
  PAR2:200-1000 nM(EC50)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Thrombin receptors, ProteaseactivatedReceptor, Protease-Activated Receptor (PAR), Protease-Activated Receptor 2, Proteaseactivated Receptor, Protease Activated Receptor (PAR), inhibit, Inhibitor, AOB 2796, AOB2796, AOB-2796, AC 55541, AC55541, AC-55541

Compound Identifiers

PubChem CID

9589606