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| Catalog Number | orb1305567 |
|---|---|
| Category | Small Molecules |
| Description | Abemaciclib |
| CAS Number | 1231929-97-7 |
| Purity | 99.87% |
| MW | 506.59 |
| SMILES | C(C)(C)N1C=2C(=C(F)C=C(C2)C3=NC(NC4=CC=C(CN5CCN(CC)CC5)C=N4)=NC=C3F)N=C1C |
| Formula | C27H32F2N8 |
| Biological Activity | Abemaciclib (LY2835219) is a dual inhibitor of CDK4/6 (IC50=2/10 nM) with selectivity and specificity. Abemaciclib has antitumor activity and is used to treat advanced or metastatic breast cancer. |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
- Item 1 of 1
- Item 1 of 1
LY2835219(Abemaciclib) [orb146246]
[1231930-82-7]
602.699
C28N8O3F2SH36
1 g, 100 mg, 250 mg, 10 mM * 1 mL in DMSO
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